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Medchemexpress LLC Anti-Mouse Galectin- 10mg | 10mg
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Anti-Mouse Galectin-9 Antibody (RG9-1) is an anti-mouse Galectin-9 IgG2b monoclonal antibody Anti-Mouse Galectin-9 Antibody (RG9-1) promotes inflammatory response by enhancing the secretion of IFN- TNF- and IL-6 Anti-Mouse Galectin-9 Antibody (RG9-1) can increase CD8 T cell and Treg frequency Anti-Mouse Galectin-9 Antibody (RG9-1) reduces graft survival time by increasing CD4 and CD8 T cell infiltration Anti-Mouse Galectin-9 Antibody (RG9-1) can be used for researches on inflammation conditions cancer and xenotransplantation such as ischemia-reperfusion colon cancer breast cancer and leukemia[1][2][3][4]
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Limaprost | 74397-12-9 | 99.9% | 50 MG
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Limaprost (OP1206) is a potent, orally active prostaglandin E1 (PGE1) analogue and vasodilator. It functions by increasing blood flow and inhibiting platelet aggregation, offering potential benefits such as pain relief and antianginal effects. This compound is suitable for research related to ischaemic symptoms.
- Potent and orally active PGE1 analogue vasodilator.
- Increases blood flow and inhibits platelet aggregation.
- Provides pain relief and antianginal effects.
- Suitable for research on ischaemic symptoms.
- Inhibits IL-1-mediated induction of nerve growth factor (NGF) in human IVD cells.
- Demonstrates in vivo efficacy in relieving Argipressin-induced ST depression.
- Increases coronary blood flow and reduces vascular resistance in animal models.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1818847-43-6 | 1-methylazetidin-3-one hydrochloride | Advanced ChemBlocks - In Stock | MFCD29060167 | 121.560 | C4H8ClNO | 97.000 | Cl.CN1CC(=O)C1 | 5g | 411177232
1-methylazetidin-3-one hydrochloride | Advanced ChemBlocks - In Stock | 1818847-43-6 | MFCD29060167 | 121.560 | C4H8ClNO | 97.000 | Cl.CN1CC(=O)C1 | 5g | 411177232
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Medchemexpress LLC Exatecan Intermediate 1-d5 | 1346617-23-9 | 99.90% | 268.28 | 25 MG
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Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1. It is for research use only and not sold to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Topoisomerase II alp | 10UL
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Topoisomerase II alp | 10UL
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Apexbio Technology LLC PX 12 141400-58-0 10mg
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PX 12 is a small-molecule inhibitor targeting thioredoxin-1 (Trx-1) It is designed to modulate cellular redox processes by inhibiting Trx-1 thereby regulating redox-sensitive signaling pathways and transcription factor activity PX 12 exerts its biological activity primarily through inhibition of Trx-1 interfering with cellular responses to hypoxia by reducing HIF-1 stabilization and subsequent VEGF expression In in vitro studies and tumor xenograft models including HT-29 and MCF-7 cell lines PX 12 demonstrates inhibitory activity Based on these pharmacological properties PX 12 holds research potential in studies of redox-regulated intracellular signaling tumor angiogenesis and vascular permeability modulation in cancer biology
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Medchemexpress LLC Ricasetron | 117086-68-7 | MFCD00866971 | 98.6% | 313.44 g/mol | C19H27N3O | 5 MG
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Ricasetron is a selective, orally active 5-HT3 receptor antagonist used in preclinical research to study serotonin receptor pharmacology. It has demonstrated antiemetic and anxiolytic activities and is supplied as a high-purity research chemical for biochemical and pharmacological assays.
- High purity suitable for research (98.6%).
- Molecular formula C19H27N3O; molecular weight 313.44 g/mol.
- Selective 5-HT3 receptor antagonist for pharmacology and preclinical studies.
- Useful as a reference compound in assays investigating antiemetic and anxiolytic effects.
- Available in small quantities appropriate for laboratory experiments.
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TARGETMOL CHEMICALS INC PF-04457845 25MG
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Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM). Purity 100%
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Apexbio Technology LLC Besifloxacin HCl 405165-61-9 500mg
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Besifloxacin HCl (CAS 405165-61-9) is a small-molecule inhibitor targeting bacterial DNA gyrase and topoisomerase IV It is designed to disrupt bacterial DNA replication and repair thereby inhibiting bacterial nucleic acid synthesis Besifloxacin HCl exerts its biological activity primarily through inhibition of DNA gyrase and topoisomerase IV In in vitro studies Besifloxacin HCl demonstrates inhibitory activity with IC50 values typically ranging from 0 1 to 0 8 g/mL depending on the specific bacterial strain tested Based on these pharmacological properties Besifloxacin HCl holds research potential in studies of antibacterial mechanisms resistance development and comparative antibiotic efficacy particularly in ocular infection models
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Aobchem AOBCHEM
5001012977 4-BROMOPHENYL 2-CHLORO-4-NIT
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Medchemexpress LLC Elovl1-IN-2 | 2761063-79-8 | 99.8% | C18H15FN2O | 50 MG
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ELOVL1-IN-2 is an inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. It exhibits weak ELOVL1 inhibition with an IC50 of 21 μM. In a primary cellular assay using HEK293 C26 cells, it shows moderate potency with an IC50 of 6.7 μM.
- ELOVL1 enzyme inhibitor
- Weak ELOVL1 inhibition (IC50 = 21 μM)
- Moderate potency in HEK293 C26 cellular assay (IC50 = 6.7 μM)
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Medchemexpress LLC Cholecystokinin (26-33) free acid | 103974-46-5 | 99.8% | 1064.19 | 5 MG
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Cholecystokinin (26-33) free acid, also known as CCK (26-33) free acid, is a cholecystokinin (CCK) fragment that can reduce food intake and gallbladder contraction. It is intended for research use only.
- Cholecystokinin fragment
- Reduces food intake
- Reduces gallbladder contraction
- For research use only
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Medchemexpress LLC Ethacridine lactate monohydrate | 6402-23-9 | 99.85% | 50 MG
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Ethacridine lactate monohydrate is a widely used antiseptic and abortifacient. It is effective against *Staphylococcus aureus* and other gram-positive cocci. It acts as a poly(ADP-ribose) glycohydrolase (PARG) inhibitor and is for research use only.
- Widely used antiseptic and abortifacient
- Effective against *Staphylococcus aureus* and other gram-positive cocci
- Acts as a poly(ADP-ribose) glycohydrolase (PARG) inhibitor
- Light yellow to yellow solid appearance
- Ships at room temperature
- Store at 4°C in sealed storage, away from moisture
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Medchemexpress LLC Prochloraz | 67747-09-5 | 99.85% | 1 G
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Prochloraz is an imidazole antifungal that functions as an estrogen receptor (ER) and androgen receptor (AR) antagonist, and an aromatase inhibitor. It strongly inhibits the microsomal cytochrome P-450 dependent 14α-demethylation of lanosterol during ergosterol biosynthesis, leading to membrane disruption and eventual cell death. In vivo, it acts as an antiandrogen by reducing reproductive organ weights, affecting androgen-regulated gene expression in the prostate, and increasing luteinizing hormone levels.
- Acts as an estrogen receptor (ER) and androgen receptor (AR) antagonist
- Functions as an aromatase inhibitor
- Activates the aryl hydrocarbon receptor (AhR)
- Inhibits ergosterol biosynthesis
- Causes membrane disruption and cell death
- Reduces reproductive organ weights in vivo
- Affects androgen-regulated gene expressions in the prostate
- Increases luteinizing hormone levels
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Sigma Aldrich Fine Chemicals Biosciences Pancuronium bromide100MG
Pancuronium bromide is a biquarternary amino steroid. It blocks muscarinic acetylcholine receptors (M2) in the heart. Pancuronium has vagolytic and sympathomimetic properties. It is associated with tachycardia and hypertension.
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